clc genomics workbench negative binomial output

A significant correlation between gene transcription patterns and phenotypic effects was found in lice collected from different salmon farms with contrasting drug treatment efficacies. rogercresseyi and tightly linked to differentially expressed coding genes. Furthermore, novel long non-coding RNAs (lncRNAs) were identified in C. Enrichment analyses of Gene Ontology terms showed specific biological processes and molecular functions associated with each delousing drug analyzed. The results revealed specific transcriptome patterns in lice exposed to azamethiphos, deltamethrin, and cypermethrin drugs. Transcriptome sequencing was conducted on samples exposed to each drug to evaluate the presence of coding and non-coding RNAs associated with the response of these compounds. Bioassays using azamethiphos, cypermethrin, and deltamethrin drugs were conducted to evaluate the sensitivity and to collect samples for RNA-sequencing. Sea lice samples from populations with contrasting sensitivity to delousing drugs were collected. This study aimed to discover novel coding genes and non-coding RNAs that could evidence drug sensitivity at the genomic level. Bioassays are commonly used to assess louse drug sensitivity, but the current procedures may mask relevant molecular responses. This pathogen is mainly controlled by immersion baths with delousing drugs, which can lead to resistant traits selection in lice populations. Caligus rogercresseyi, commonly known as sea louse, is an ectoparasite copepod that impacts the salmon aquaculture in Chile, causing losses of hundreds of million dollars per year.

Clc genomics workbench negative binomial output